Prolonged survival and pulmonary metastasis after local cure of glioblastoma multiforme

A 59-year-old woman underwent a frontal lobectomy and irradiation for a gli oblastoma multiforme, with further craniotomies to drain postoperative subd ural and extradural infections. She survived for 5 years after the initial operation, but died as a result of pulmonary metastatic tumors, At post-mor tem examination no residual intracranial tumor could be found. The pulmonar y tumors were metastases from the glioblastoma, Prolonged survival, extrane ural metastasis and curative local treatment are each uncommon in glioblast oma, but all occurred in this patient.