Convergence of multilocus systems under weak epistasis or weak selection

Citation
T. Nagylaki et al., Convergence of multilocus systems under weak epistasis or weak selection, J MATH BIOL, 38(2), 1999, pp. 103-133
Citations number
45
Categorie Soggetti
Multidisciplinary
Journal title
JOURNAL OF MATHEMATICAL BIOLOGY
ISSN journal
03036812 → ACNP
Volume
38
Issue
2
Year of publication
1999
Pages
103 - 133
Database
ISI
SICI code
0303-6812(199902)38:2<103:COMSUW>2.0.ZU;2-E
Abstract
The convergence of multilocus systems under viability selection with consta nt fitnesses is investigated. Generations are discrete and nonoverlapping; the monoecious population mates at random. The number of multiallelic loci, the linkage map, dominance, and epistasis are arbitrary. It is proved that if epistasis or selection is sufficiently weak (and satisfies a certain no ndegeneracy assumption whose genericity we establish), then there is always convergence to some equilibrium point. In particular, cycling cannot occur . The behavior of the mean fitness and some other aspects of the dynamics a re also analyzed.