Effect of electrospray needle voltage on electroosmotic flow in capillary electrophoresis-mass spectrometry

Authors
Lazar, IM Lee, ML
Citation
Im. Lazar et Ml. Lee, Effect of electrospray needle voltage on electroosmotic flow in capillary electrophoresis-mass spectrometry, J AM SOC M, 10(3), 1999, pp. 261-264
Citations number
16
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
ISSN journal
10440305 → ACNP
Volume
10
Issue
3
Year of publication
1999
Pages
261 - 264
Database
ISI
SICI code
1044-0305(199903)10:3<261:EOENVO>2.0.ZU;2-1
Abstract
The effect of the electrospray ionization (ESI) needle voltage on the elect roosmotic flow (EOF) in capillary electrophoresis (CE)-mass spectrometry (M S) was investigated. The radial electric field that penetrates across the C E capillary wall imposed by the ESI-needle voltage modifies the typical EOF . This effect was investigated for buffers commonly used in CE-MS. Variatio ns as high as -/+30% were observed. (C) 1999 American Society for Mass Spec trometry.