Cross-action of extracellular stress adaptation factors in microorganisms

The ability of microorganisms from different taxa to adapt to stress condit ions by means of extracellular factors exhibiting similar mechanisms of act ion was demonstrated. The action of adaptation factors synthesized by the e nteric bacterium Escherichia coil, the soil bacterium Bacillus subtilis, an d the yeast Candida utilis was characterized in biological tests. It was de monstrated that the factor of accelerated adaptation to new media (FAANM) a nd the growth-rate-reducing factor (factor X-II), which decreases the rate of exponential culture growth, were synthesized by all microorganisms teste d. Antilysin (factor X-I), which accelerates cell adaptation to N-ethylmale imide, was not produced by C. utilis.