Chemosensory perception in the gut

Citation
D. Hofer et al., Chemosensory perception in the gut, NEWS PHYSL, 14, 1999, pp. 18-23
Citations number
15
Categorie Soggetti
Physiology
Journal title
NEWS IN PHYSIOLOGICAL SCIENCES
ISSN journal
08861714 → ACNP
Volume
14
Year of publication
1999
Pages
18 - 23
Database
ISI
SICI code
0886-1714(199902)14:<18:CPITG>2.0.ZU;2-6
Abstract
The ability of the gut mucosa to sense the chemical composition of chyme is important for gastrointestinal functions. The demonstration of gustducin a nd transducin, two alpha-subunits of GTP-binding proteins involved in gusta tory signal transduction, in gastrointestinal epithelial cells provides fir st clues to the molecular basis of enteric chemosensitivity. Nitric oxide m ay play a role as a secondary messenger.