A newborn infant with seizures of unknown etiology that were refractory to
treatment with phenobarbitone, phenytoin, midazolam, clonazepam, and vigaba
trin is reported. The introduction of the new antiepileptic drug lamotrigin
e was followed by rapid and sustained control of the seizures. (C) 1999 by
Elsevier Science Inc. All rights reserved.