A detailed anatomic and intramuscular neural staining study in 22 human and
5 monkey upper limbs revealed that the flexor carpi radialis can be raised
on its proximal neurovascular pedicle and that the muscle can be split alo
ng its tendon into two independently functioning neuromuscular compartments
, each with its own nerve and blood supply. A study of the muscle architect
ure in the human specimens found the radial compartment to have significant
ly longer fiber length and a larger physiologic cross-sectional area than t
he ulnar compartment. Independence of function of each compartment was demo
nstrated in electrical stimulation studies in six monkeys (Macaca fascicula
ris), but no significant difference was noted in the peak isometric load be
tween the two compartments (p = 0.68) in the monkey. The extra functioning
muscle units become important in local transfers for restoring function in
multiple nerve Daisies as in Hansen's disease, severe traumatic loss of mus
cle in crush injuries and compartment syndromes, and after wide resection i
n infective and neoplastic conditions in the forearm and hand.