Reluctance of the lay public to perform bystander CPR is becoming an increa
singly worrisome problem in the USA. Most bystanders who admit such relucta
nce concede that fear of contagious disease from mouth-to-mouth contact is
what keeps them from performing basic life support. Animal models of prehos
pital cardiac arrest indicates that 24-h survival is essentially as good wi
th chest compression-only CPR as with chest compressions and assisted venti
lation. This simpler technique is an attractive alternative strategy for en
couraging more bystander participation. Such experimental studies have been
criticized as irrelevant however secondary to differences between human an
d porcine airway mechanics. This study examined the effect of chest compres
sion-only CPR under the worst possible circumstances where the airway was t
otally occluded. After 6 min of either standard CPR including ventilation w
ith a patent airway or chest compressions-only with a totally occluded airw
ay, no difference in 24 h survival was found (10/10 vs. 9/10). As anticipat
ed arterial blood gases were not as good, but hemodynamics produced were be
tter with chest compression-only CPR (P < 0.05). Chest compression-only CPR
, even with a totally occluded airway, is as good as standard CPR for succe
ssful outcome following 6.5 min of cardiac arrest. Such a strategy for the
first minutes of cardiac arrest, particularly before professional help arri
ves, has several advantages including increased acceptability to the lay pu
blic. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.