CONSOLIDATION PARAMETERS OF MALTODEXTRINS OBTAINED FROM COMPRESSION-DECOMPRESSION FIXED STRESS RATE

Compression-decompression fixed stress rate at 0.5 and 5 MPa/s has bee n used to obtain maltodextrin compacts. Indentation hardness of tablet surfaces has been used to determine the consolidation mechanisms of m altodextrins for direct compression. The compressibility and compactib ility of the powders have been determined using an equation previously described. Also, parameters obtained from Heckel tablet-in-die and ej ected-tablet methods were calculated. The strain rate sensitivity (SRS ) was calculated for both excipients, as well. Methods based on indent ation hardness in these materials were less dependent on the compressi on speed. Also. SRS calculated with yield pressure obtained from these cycles gave adequate without higher differences in compaction speed.