Simple and highly enantioselective nonenzymatic ring opening of cyclic prochiral anhydrides

Authors
Bolm, C Gerlach, A Dinter, CL
Citation
C. Bolm et al., Simple and highly enantioselective nonenzymatic ring opening of cyclic prochiral anhydrides, SYNLETT, (2), 1999, pp. 195-196
Citations number
19
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
2
Year of publication
1999
Pages
195 - 196
Database
ISI
SICI code
0936-5214(199902):2<195:SAHENR>2.0.ZU;2-0
Abstract
A convenient highly enantioselective methanolysis of cyclic meso-anhydrides only requires one equivalent cinchona alkaloid and low temperature. Both e nantiomers can be easily obtained with up to 98% ee by using either quinine or quinidine.