J. Zhou et al., Facile and stereospecific synthesis of cis-3-(N '-arylureido)-2,3-dihydro-2-phenyl-1,2-benzoxaphosphole 2-oxides, SYNTHESIS-S, (2), 1999, pp. 234-236
A simple method for the preparation of cis-3-(N'-aryl-ureido)-2,3-dihydro-2
-phenyl-1,2-benzoxaphosphole 2-oxides 7 in moderate to high yields consists
in the three-component reaction of phenyldichlorophosphine with salicylald
ehyde and arylureas in anhydrous benzene. The stereochemistry and the possi
ble reaction mechanism of the cyclizations are also discussed. The results
presented in this paper provide a new general and efficient approach to the
novel organophosphorus heteracycles with the 3-substituted 2,3-dihydro-1,2
-benzoxaphosphole 2-oxide ring system.