Neopentyl and neophyl groups: New nontransferable groups for organocopper and organozine chemistry

Authors
Lutz, C Jones, P Knochel, P
Citation
C. Lutz et al., Neopentyl and neophyl groups: New nontransferable groups for organocopper and organozine chemistry, SYNTHESIS-S, (2), 1999, pp. 312-316
Citations number
20
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
2
Year of publication
1999
Pages
312 - 316
Database
ISI
SICI code
0039-7881(199902):2<312:NANGNN>2.0.ZU;2-I
Abstract
Neopentyl and Neophyl groups have been found to be excellent nontransferabl e groups for organozinc and organocopper chemistry. We have shown that mixe d diorganozincs of the type FG-R-Zn(CH2CMe2R) can be used advantageously fo r the enantioselective addition to aldehydes. These mixed copper or zinc re agents are also found to be very efficient in the Michael addition to vario us activated alkenes.