A. Kitamura et al., Echinoclathrines A-C: a new class of pyridine alkaloids from an Okinawan sponge, Echinoclathria sp, TETRAHEDRON, 55(9), 1999, pp. 2487-2492
Echinoclathrines A-C (3 - 5) have been isolated from an Okinawan sponge, Ec
hinoclathria sp. and the structures elucidated by interpretation of spectra
l data These compounds are a new class of pyridine alkaloids possessing an
4-aryl-2-methylpyridine moiety as a common structural element. Echinoclathr
ines A and B exhibited weak immunosuppressive activity in a mixed lymphocyt
e reaction assay. (C) 1999 Elsevier Science Ltd. All rights reserved.