Studies toward the synthesis of natural and unnatural dienediynes 1. Approaches to a functionalised bicyclic ring system

Authors
Caddick, S Delisser, VM Doyle, VE Khan, S Avent, AG Vile, S
Citation
S. Caddick et al., Studies toward the synthesis of natural and unnatural dienediynes 1. Approaches to a functionalised bicyclic ring system, TETRAHEDRON, 55(9), 1999, pp. 2737-2754
Citations number
29
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
9
Year of publication
1999
Pages
2737 - 2754
Database
ISI
SICI code
0040-4020(19990226)55:9<2737:STTSON>2.0.ZU;2-U
Abstract
The synthesis of a functionalised bicyclic ring system related to the natur ally occurring dienediynes, NCS and Kedarcidin Chromophores is presented. K ey steps involve: conjugate addition of an enediyne to a functionalised eno ne and intramolecular boron mediated aldol reaction. (C) 1999 Elsevier Scie nce Ltd. All rights reserved.