S. Arseniyadis et al., Studies towards the total synthesis of taxoids: a rapid entry into bicyclo[6.4.0]dodecane ring system. Part 2, TETRAHEDR-A, 10(1), 1999, pp. 193-206
We report a synthetic route that allows access into A-seco taxoid framework
s embodying the entire carbon skeleton and a large number of oxygen functio
nalities. The BC-subunit (-)-4 was constructed in five steps from (+)-3, th
rough a step-efficient and stereocontrolled bond construction. (C) 1999 Els
evier Science Ltd. All rights reserved.