Cytogenetic analysis of a juxta-articular myxoma revealed two distinct cyto
genetically abnormal cell populations: inv(2)(p15q36) and +7, t(8;22)(q11-1
2; q12-13). These clonal chromosomal changes, the first to be reported in t
his tumour type, suggest that at least some juxta-articular myxomas are neo
plastic rather than reactive in nature.