The molecular recognition of nucleotide phosphate and fluorescence chemosensor

A new fluorescence chemical sensor-compound 1 used for identification of nu cleotide phosphate such as ATP, ADP, AMP anion in water has been synthesize d, According to the variation of pyrene excimer emission of compound 1 in w ater with concentration of nucleotide phosphates and adenine, the quenching constants have been measured, In addition, the stability constants of the complexes between compound 1 and different nucleotide phosphate have also b een determined, From the results, compound 1 shows a better selectivity for ATP than for ADP or AMP, Moreover, the molecular configuration and molecul ar geometrical size of compound 1 and its complexes calculated by the metho d of molecular mechanics were compared and studied with experimental result s.