Catatonia under medication with risperidone in a 61-year-old patient

This report describes the case of a 61-year-old female schizophrenic patien t with status post-frontal lobotomy some 35 years ago with prominent parano id delusions. This woman developed severe catatonia under medication with a serotonergic/dopaminergic neuroleptic, risperidone, at a dose of up to 5 m g daily. The catatonic disorder was dose-dependent and subsided immediately after switching the medication to another atypical antipsychotic, clozapin e. Given the negative history for catatonia in this patient, the temporal c oincidence of administration of risperidone and catatonia is a novel findin g.