Available epidemiologic data on the occurrence of house-dust mites in dwell
ings demonstrates a clear association between increased indoor air humidity
and the increased occurrence of house-dust mites in house dust. Furthermor
e, in temperate climates, there is a threshold level of indoor air humidity
of 7 g/kg (45% relative humidity at usual indoor air temperatures). Indoor
air humidities below this level for extended periods will eradicate house-
dust mites from dwellings. A reduction in inhabitant exposure to house-dust
mites is implemented by reduction of indoor air humidity by controlled mec
hanical ventilation. Individual ventilation levels are estimated from the a
ctual size of house, number of inhabitants, and average outdoor air humidit
y in winter. In contrast, more humid areas of the world with average outdoo
r humidities above 6-7 g/kg in winter will support uniformly large populati
ons of house-dust mites, and reductions in indoor air humidity will have a
comparatively minor effect on the occurrence of house-dust mites. Present-d
ay building of energy-efficient houses with increased sealing of the buildi
ng envelope, paralleled by a similar renovation of older houses, has increa
sed indoor air humidity and is probably the cause of the almost fourfold in
crease in the occurrence of house-dust mites in Danish dwellings.