Rhinological problems after a transseptal transsphenoidal approach for pitu
itary tumors were prospectively investigated in 25 patients with special re
ference to nasal airway, resistance and olfactory acuity. Five patients sho
wed a significant increase in the unilateral and/or total nasal airway resi
stance. Endoscopic observation of the nasal cavity revealed the presence of
crust formation, hypertrophy of the inferior turbinate, or synechiae. Thre
e patients showed a significant deterioration in olfactory acuity. Coronal
CT views with good visualization of the olfactory cleft were helpful in eva
luating causes of hyposmia postoperatively.