Congenital transmission of Schistosoma japonicum in pigs was investigated b
y experimentally infecting sows at four weeks gestation (n = 3), 10 weeks g
estation (n = 3), or a few weeks prior to insemination (n = 2). None of the
piglets born to sows infected prior to insemination or in early pregnancy
were found to be infected. However, all of the piglets (n = 26) born to sow
s infected at 10 weeks gestation were found to harbor schistosomes with S.
japonicum eggs recovered from both their feces and livers, The findings sho
w that congenital S. japonicum infection of pigs can occur if sows are infe
cted during mid-to-late pregnancy and may have important implications not o
nly for pigs but also for other mammalian hosts of schistosomes, including
humans.