Ac. Beekley et al., Malignant eccrine spiradenoma: A previously unreported presentation and review of the literature, AM SURG, 65(3), 1999, pp. 236-240
Malignant eccrine spiradenomas (MESs) are rare tumors arising from previous
ly benign eccrine spiradenomas. A review of the literature reveals only 25
published reports of malignancy arising from eccrine spiradenoma and no pri
or reports of an MES of the scalp, The tumors have a metastasis rate of >50
per cent in reported cases with high resultant mortality rates, We present
the first case report of a single MES of the scalp, Multiple resections we
re required for local control, Both magnetic resonance imaging and lymphosc
intigraphy were used to assess regional spread. A review of the literature
follows to include histopathology, diagnosis, and both surgical and adjuvan
t therapeutic options.