Neoplastic involvement of the pericardium resulting in an effusion and subs
equent tamponade is an emergency requiring prompt decompression, generally
safely accomplished by subxiphoid pericardiectomy. However, the current cas
e report describes a patient with florid pericardial tamponade who underwen
t surgical decompression with transient hemodynamic improvement, who then r
apidly developed progressive, heart failure and death. This paradoxical res
ponse to pericardial decompression, similar to that seen occasionally with
pericardiectomy in constrictive pericarditis, may be more frequent than cur
rently appreciated. Its cause may relate to the sudden removal of the chron
ic external ventricular support from the effusion resulting in ventricular
dilatation and failure. (C) 1999 by The Society of Thoracic Surgeons.