Infiltrative endometriosis is an uncommon condition that may involve all pe
lvic organs and is associated with considerable morbidity. A small percenta
ge of patients will have disease that is unresponsive to hormonal therapy a
nd is unsuitable for conservative surgery. Presented is a review of 5 case
reports of patients who required radical surgery for control of symptoms ca
used by endometriosis. Radical surgery was associated with minimal morbidit
y and a high rate of resolution of symptoms. Radical surgery should be cons
idered as part of the treatment strategy particularly when there is evidenc
e of endometriosis invading into the adjacent gastrointestinal tract or uri
nary tract.