Methylation of tea catechins by rat liver homogenates

Citation
K. Okushio et al., Methylation of tea catechins by rat liver homogenates, BIOS BIOT B, 63(2), 1999, pp. 430-432
Citations number
17
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
63
Issue
2
Year of publication
1999
Pages
430 - 432
Database
ISI
SICI code
0916-8451(199902)63:2<430:MOTCBR>2.0.ZU;2-P
Abstract
Methylation of(-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECg), an d (-)-epigallocatechin gallate (EGCg) was carried out with a rat liver homo genate and S-adenosyl-L-methionine. A structural analysis of the reaction p roducts by MS and NMR showed that 4'-O-methyl EGG, 4 "-O-methyl ECg, and 4 "-O-methyl EGCg had been formed from EGG, ECg, and EGCg, respectively. Thes e results suggest that methylation may be one of the metabolic pathways to the catechins.