J. Van Loo et al., Functional food properties of non-digestible oligosaccharides: a consensusreport from the ENDO project (DGXII AIRII-CT94-1095), BR J NUTR, 81(2), 1999, pp. 121-132
This paper results from the final phase of the ENDO project (DGXII AIRII-CT
94-1095), a European Commission-funded project on non-digestible oligosacch
arides (NDO). All participants in the programme met to perform a consensus
exercise on the possible functional food properties of NDO. Topics studied
during the project (including a workshop on probiotics and prebiotics) and
related aspects, for which considerable evidence has been generated recentl
y, were evaluated on the basis of existing published scientific evidence. T
here was a general consensus that: (1) there is strong evidence for a prebi
otic effect of NDO in human subjects. A prebiotic effect was defined as a f
ood-induced increase in numbers and/or activity predominantly of bifidobact
eria and lactic acid bacteria in the human large intestine; (2) there is st
rong evidence for the impact that NDO have on bowel habit; (3) there is pro
mising evidence that consumption of inulin-type fructans may result in incr
eased Ca absorption in man; (4) there are preliminary indications that inul
in-type fructans interact with the functioning of lipid metabolism; (5) the
re is preliminary evidence in experimental animals of a preventive effect a
gainst colon cancer. Human nutrition studies are needed to substantiate the
se findings, it was concluded that the nutritional properties of NDO may pr
ove to be a key issue in nutritional research in the future.