Peptide mapping is common techique used for studying proteins. Such methods
can explain small changes in the structure of the protein molecule. The ar
ticle deals with various types of methods which are used for this purpose.
The article describes first hydrolysis of different enzymes or degradation
with cyanogen bromide, then separation of peptide fragments (by chromatogra
phy and electrophoresis). Finally, the separated peptides are detected. The
individual steps of the technique are reviewed.