Application of polymer supported base in solid phase synthesis: Convenientsynthesis of N-aryl-N '-benzyl piperazine derivatives

Authors
Yamamoto, Y Tanabe, K Okonogi, T
Citation
Y. Yamamoto et al., Application of polymer supported base in solid phase synthesis: Convenientsynthesis of N-aryl-N '-benzyl piperazine derivatives, CHEM LETT, (2), 1999, pp. 103-104
Citations number
7
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY LETTERS
ISSN journal
03667022 → ACNP
Issue
2
Year of publication
1999
Pages
103 - 104
Database
ISI
SICI code
0366-7022(199902):2<103:AOPSBI>2.0.ZU;2-4
Abstract
N-Aryl-N'-benzyl piperazine derivatives were synthesized using REM resin. I n cleavage step, the piperazine derivatives were successfully prepared in a good yield and excellent purity by treatment with novel polymer supported base in the absence of any base.