The radical changes made in the delivery of modern health care have serious
implications for laboratory services, because reasoning in laboratory medi
cine should follow a clinical rather than a technological logic. Appropriat
e test requesting and interpretation coupled with a patient-oriented vision
improve the outcomes for patients, and so ensure the best cost containment
strategy. The fact that analytical operations are standardized and quality
controlled, may lead to a greater recognition of the importance of pre- an
d post-analytical issues. Particularly critical aspects are the formulation
of the clinical question and the interpretation of laboratory results. Lab
oratory-clinic communication is fundamental in achieving and maintaining to
tal quality in laboratory services. Effective consultancy stands or falls w
ith the knowledge and experience of laboratorians, as well as continuous ed
ucation is required to maintain the best utilization of laboratory informat
ion in clinical decision-making. As clinical audit is an important tool for
reviewing and improving the quality of the service in clinical laboratorie
s, it should make up an important part of programs for accreditation and qu
ality improvement. If a patient-centered vision predominates, the clinical
laboratory will be linked to both physicians and patients, making it more t
angible to the latter. (C) 1999 Elsevier Science B.V. All rights reserved.