Adult onset of multifocal eosinophilic granuloma of bone: A longterm follow-up with evaluation of various treatment options and spontaneous healing

We report a case of multifocal-monosystemic Langherhans cell histiocytosis (LCH), formerly usually referred to as eosinophilic granuloma (EG) of bone. The condition developed in a 36-year-old man. A notable infrequent thoraci c spine location and two successive distinct costal lesions were observed. Both the first costal site and the vertebral location healed spontaneously; the second costal lesion underwent biopsy resection. The patient's disease course with an 8-year follow-up is discussed with reference to various tre atment options, emphasising in selected cases a watchful conservative appro ach, in view of the widely documented potential for spontaneous healing.