Simple standardised neuropsychological assessments aid in the differentialdiagnosis of dementia with Lewy bodies from Alzheimer's disease and vascular dementia
Cg. Ballard et al., Simple standardised neuropsychological assessments aid in the differentialdiagnosis of dementia with Lewy bodies from Alzheimer's disease and vascular dementia, DEMENT G C, 10(2), 1999, pp. 104-108
Consecutive patients from a dementia case register received a standardised
evaluation which incorporated a neuropsychological assessment with the Camb
ridge Assessment for disorders in the elderly (CAMCOG). Operationalised cli
nical diagnoses were made (consensus criteria for dementia with Levy, bodie
s, DLB; NINCDS-ADRDA for Alzheimer's disease, AD, NINCDS AIRENS for vascula
r dementia, VaD), Two-hundred and twenty-eight patients were studied (DLB 5
4, AD102, VaD 72), DLB patients had significantly better performance on rec
ent memory than AD patients, but more impaired visuospatial praxis. DLB pat
ients also had significantly better recent memory than those with VaD, Opti
mal cut-off points for the recent memory:praxis ratio achieved good discrim
ination between DLB and both other dementias.