We conducted a retrospective cohort study to examine whether patients with
Alzheimer's disease (AD) or vascular dementia (VaD) differed in the number
and type of associated comorbid conditions, In addition, we evaluated the i
mpact of the severity of cognitive impairment on hospitalization and mortal
ity of patients in each group. We studied 161,106 patients over age 65, wit
h any degree of cognitive impairment, residing in any of 1,573 Medicare/Med
icaid-certified nursing homes of 5 states of the USA between 1992 and 1995.
Patients were assessed with the federally mandated Minimum Data Set (MDS),
The MDS has been cross-linked to Medicare eligibility files and to the Med
icare Provider Analysis and Review database. AD patients were younger, and
more likely to be female and Caucasian than VaD patients. For comparable le
vels of cognitive impairment, AD patients appeared to have fewer comorbid c
onditions, including those that were not risk factors for VaD. In addition,
patients with AD had decreased morbidity and mortality relative to patient
s with VaD. These findings support the hypothesis that AD patients are a he
althier group of demented patients.