Particle size distributions in mesh cuts and microscopically estimated volumetric shape factors

Citation
Jt. Carstensen et M. Dali, Particle size distributions in mesh cuts and microscopically estimated volumetric shape factors, DRUG DEV IN, 25(3), 1999, pp. 347-352
Citations number
12
Categorie Soggetti
Pharmacology & Toxicology
Journal title
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
ISSN journal
03639045 → ACNP
Volume
25
Issue
3
Year of publication
1999
Pages
347 - 352
Database
ISI
SICI code
0363-9045(1999)25:3<347:PSDIMC>2.0.ZU;2-X
Abstract
When particle size distribution parameters are calculated from sieve analys is, it is generally assumed that the distribution within the particle cut i s either linear producing a mean particle size equal to the average of the mesh openings (1-3), or that a more proper number is the geometric mean of these two apertures. It is shown here that particles within a mesh cut are not linearly distributed, but rather may be normally, log-normally or bipha sic combinations of the two. Three compounds were examined in this fashion, and results are reported here.