Tissue distribution and functional contribution of P2X receptors in the CNS

Authors
Robertson, SJ
Citation
Sj. Robertson, Tissue distribution and functional contribution of P2X receptors in the CNS, DRUG DEV R, 45(3-4), 1998, pp. 336-341
Citations number
52
Categorie Soggetti
Pharmacology & Toxicology
Journal title
DRUG DEVELOPMENT RESEARCH
ISSN journal
02724391 → ACNP
Volume
45
Issue
3-4
Year of publication
1998
Pages
336 - 341
Database
ISI
SICI code
0272-4391(199811/12)45:3-4<336:TDAFCO>2.0.ZU;2-A
Abstract
Since the identification of a P2X receptor-mediated central synapse in 1992 and the initial cloning of the P2X receptors in 1994 there has been great interest in the possible functions of P2X receptors in the CNS, The purpose of this review is not to detail every study but to highlight recent advanc es and try and compare physiological function of P2X receptors with recepto r composition in the CNS, Drug Dev. Res. 45:336-341, 1998. (C) 1998 Wiley-L iss, Inc.