The prevalence of adult obesity in Kuwait is among the highest in the Arab
peninsula, and cardiovascular disease, for which obesity is a risk factor,
is the leading cause of death. This study reports familial and environmenta
l factors associated with childhood obesity; in addition to adverse effects
of obesity on children's serum lipids, lipoproteins, apolipoproteins, insu
lin, and blood pressure profiles. The authors carried out a pair-matched ca
se-control study including 460 obese (body mass index >90th percentile of t
he age/sex specific reference value of the National Center for Health Stati
stics), school children 6 to 13 years old matched by age and gender to 460
normal weight controls. We ascertained obese children in a cross-sectional
survey of a representative sample of 2400 school children selected from 20
schools by multistage stratified random sampling. Biochemical variables and
blood pressure were adversely affected in obese children. The conditional
logistic regression analysis showed that family history of obesity, and dia
betes mellitus, respiratory and bone diseases in child were significant ass
ociated factors with obesity after adjusting for social and behavioural fac
tors. Physical activity and parental social class were not significant. We
recommend early preventive measures with emphasis on families in which one
or both parents are overweight.