Recurrent clear cell carcinoma of the ovary changing into producing parathyroid hormone-related protein (PTH-rP) with hypercalcemia

Authors
Koshiyama, M Fujii, H Konishi, M Nanno, H Hayashi, M Tauchi, K Yoshida, M
Citation
M. Koshiyama et al., Recurrent clear cell carcinoma of the ovary changing into producing parathyroid hormone-related protein (PTH-rP) with hypercalcemia, EUR J OB GY, 82(2), 1999, pp. 227-229
Citations number
14
Categorie Soggetti
Reproductive Medicine
Journal title
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY
ISSN journal
03012115 → ACNP
Volume
82
Issue
2
Year of publication
1999
Pages
227 - 229
Database
ISI
SICI code
0301-2115(199902)82:2<227:RCCCOT>2.0.ZU;2-#
Abstract
We experienced the case of a clear cell carcinoma of the ovary arising from an endometrial cyst, which started to produce parathyroid hormone-related protein (PTH-rP) in a recurrent tumor; thus inducing hypercalcemia. Using i mmunohistochemical analysis, we demonstrated that the primacy carcinoma was immunonegative for PTH-rP, but that the recurrent carcinoma was strongly i mmunopositive for PTH-rf. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.