Erythrocyte sodium and Na+,K+-ATPase activity in untreated hypertensives and their first degree relatives

Authors
Sudhakar, K Sujatha, M Devi, CVR Reddy, PP
Citation
K. Sudhakar et al., Erythrocyte sodium and Na+,K+-ATPase activity in untreated hypertensives and their first degree relatives, I J BIOCH B, 35(6), 1998, pp. 382-384
Citations number
23
Categorie Soggetti
Biochemistry & Biophysics
Journal title
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS
ISSN journal
03011208 → ACNP
Volume
35
Issue
6
Year of publication
1998
Pages
382 - 384
Database
ISI
SICI code
0301-1208(199812)35:6<382:ESANAI>2.0.ZU;2-F
Abstract
In this paper we report the erythrocyte sodium concentration and Na+, K+-AT Pase activity in 86 untreated hypertensives and their 77 first degree relat ives and also in sex and age matched controls. There was significant increa se in erythrocyte sodium both in the hypertensives and their first degree r elatives (p < 0.01), whereas Na+, K+-ATPase activity was significantly redu ced in the study group when compared with controls. The possibility of usin g these parameters as genetic markers is suggested.