converting from paraocular to topical anesthesia in cataract surgery and to
evaluate patient pain and satisfaction with each procedure.
Setting: Department of Ophthalmology, Helsinki University Central Hospital,
Helsinki, Finland.
Methods: Three hundred eyes of 245 consecutive patients were prospectively
assigned by permuted block-restricted randomization to receive topical (bup
ivacaine 0.75%) (Group 1; n = 136) or paraocular (Group 2; n = 163) anesthe
sia. The intraoperative conditions were judged by the surgeon. A numerical
scale (0 to 10) was used to assess the degree of pain during administration
of anesthesia, during surgery and 1 and 24 hours postoperatively. Outcome
measures were the number of complications and adverse events registered per
ioperatively and 4 months postoperatively as well as Snellen visual acuity
and surgically induced astigmatism (SIA) measured I week and 4 months after
surgery.
Results: The success of posterior chamber intraocular lens (IOL) implantati
on through a self-sealing clear corneal incision was very high (99.3% and 9
6.9% in Groups 1 and 2, respectively). One case (0.7%) in the topical group
required vitrectomy and implantation of an anterior chamber IOL. Anesthesi
a-related difficulties were reported in about 40% of patients in Group 1 an
d 4% in Group 2 (P < .001). Supplemental paraocular anesthesia was required
in 4 cases (2.9%) in the topical group. Sedative/analgesic medication give
n perioperatively was required significantly more often in Group 1 (13.2%)
than in Group 2 (2.4%) (P < .01). Significantly more pain during surgery (P
< .001) and 1 hour after surgery (P < .001) was reported in the topical gr
oup. In Group 1 69.9% and in Group 2 93.3% reported no pain during surgery
(P < .001). Chemosis (1.8%), subconjunctival hemorrhage (1.2%), and periorb
ital hematoma (1.2%) were seen only in the paraocular group. Perioperativel
y, no severe complications occurred in Group 1 and the number of adverse ev
ents was less than in Group 2. Postoperatively, 2 cases of endophthalmitis
developed in the topical group and none in the paraocular group. There was
no between-group difference in outcome measures; a visual acuity of 20/40 o
r better was found in 87.8% of eyes in Group 1 and 84.9% in Group 2 4 month
s postoperatively, and the percentages of eyes with SIAs within 1.0 diopter
of preoperative values were similar (78.8% and 73.3%, respectively). Patie
nt preference for topical anesthesia appeared to be higher than for paraocu
lar anesthesia.
Conclusion: Paraocular anesthesia gave better analgesia than topical, but t
opical anesthesia provided acceptable analgesia during surgery and showed t
hat intraocular procedures can be performed without akinesia. The surgeon c
onverting to topical anesthesia may expect slight difficulty in 40% of case
s and more severe difficulty in 7%. Surgically related complications were s
imilar with both methods.