M. Sugahara et T. Ukita, A FACILE COPPER-CATALYZED ULLMANN CONDENSATION - N-ARYLATION OF HETEROCYCLIC-COMPOUNDS CONTAINING AN -NHCO- MOIETY, Chemical and Pharmaceutical Bulletin, 45(4), 1997, pp. 719-721
N-Aryl heterocyclic compounds were synthesized from aryl halides and h
eterocyclic compounds containing an -NHCO- moiety by using a catalytic
amount (1-10 mol%) of a commercially available copper catalyst in sat
isfactory yields. This catalytic reaction was applicable to the synthe
sis of N-aryl-2-pyridone, -2-pyrrolidone,-1(2H)-isoquinolone, -1(2H)-p
hthalazinone, -4(3H)-quinazolinone and -1,2,3-benzotriazin-4(3H)-one d
erivatives.