11-isopropylcryptolepine: A novel alkaloid isolated from Cryptolepis sanguinolenta characterized using submicro NMR techniques

Authors
Hadden, CE Sharaf, MHM Guido, JE Robins, RH Tackie, AN Phoebe, CH Schiff, PL Martin, GE
Citation
Ce. Hadden et al., 11-isopropylcryptolepine: A novel alkaloid isolated from Cryptolepis sanguinolenta characterized using submicro NMR techniques, J NAT PROD, 62(2), 1999, pp. 238-240
Citations number
27
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
62
Issue
2
Year of publication
1999
Pages
238 - 240
Database
ISI
SICI code
0163-3864(199902)62:2<238:1ANAIF>2.0.ZU;2-9
Abstract
A new alkaloid has been isolated from extracts of the West African plant Cr yptolepis sanguinolenta and identified by submicro NMR techniques as 11-iso propylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the indolo[3,2-b]quinoline nucleus is suggestive of a m ixed biosynthetic origin for the alkaloid.