Norpregnane glycosides from a Thai soft coral, Scleronephthya pallida

Authors
Kittakoop, P Suttisri, R Chaichantipyuth, C Vethchagarun, S Suwanborirux, K
Citation
P. Kittakoop et al., Norpregnane glycosides from a Thai soft coral, Scleronephthya pallida, J NAT PROD, 62(2), 1999, pp. 318-320
Citations number
15
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
62
Issue
2
Year of publication
1999
Pages
318 - 320
Database
ISI
SICI code
0163-3864(199902)62:2<318:NGFATS>2.0.ZU;2-6
Abstract
Two new norpregnane glycosides, 19-norpregna-1,3,5(10),20-tetraen-3-O-alpha -fucopyranoside (3) and 19-norpregna-1,3,5(10),20-tetraen-3-O-beta-arabinop yranoside (4), were isolated from the soft coral Scleronephthya pallida, al ong with two known steroids, pregna-1,20-dien-3-one (1) and 19-norpregna-1, 3,5(10),20-tetraen-3-ol (2). 19-Norpregna-1,3,5(10),20-tetraen-3-O-alpha-fu copyranoside (3) exhibits moderate antimalarial and cytotoxic activities. T he chemical structures of 1-4 were elucidated from spectroscopic data.