7-Epiclusianone, isolated from Rheedia gardneriana was tested in several bi
ological assays. It was active in vitro against trypomastigotes of Trypanos
oma cruzi but inactive in vivo in experimentally infected mice. It was also
active against Artemia salina, but inactive against the fungus Cladosporiu
m sphaerospermum and the snail Biomphalaria glabrata.