Am. Alobaid, PMR SPECTROMETRIC ASSAY OF METHOXAMINE HCL IN BULK DRUGS AND PHARMACEUTICAL FORMULATIONS, Journal of the Chemical Society of Pakistan, 18(4), 1996, pp. 302-305
A simple, accurate and rapid PMR method for the determination of metho
xamine HCl has been developed. The relative standard deviations or coe
fficient of variation CV are +/- 1.22% and 1.42% for the pure drug and
injections, respectively. The results for authentic sample and inject
ions are comparable to those obtained using the official B.P. 1988 met
hod where relative standard deviation is 0.85%. There was no evidence
of interference from the excipients. In addition, the PMR spectrum fur
nishes a specific mean of identification of methoxamine.