Increased dermal angiogenesis after low-intensity laser therapy for a chronic radiation ulcer determined by a video measuring system

Acute and chronic radiation-induced dermatitis can occur after high doses o f ionizing radiation of the skin. We describe a patient with a long-lasting radiotherapy-induced ulcer that healed after low-intensity laser therapy. A video measuring system was used to determine the number of dermal vessels in the ulcer before and after laser treatment. We found a statistically si gnificant increase in the number of dermal vessels after low-intensity lase r therapy in both the central and marginal parts of the ulcer compared with its pretreatment status.