Ww. Wardakhan et al., Reaction of 4-aryl-3-thiosemicarbazides with phenylisothiocyanate: A facile synthesis of thiazole, pyrazole and pyrimidine derivatives, J CHIN CHEM, 46(1), 1999, pp. 97-104
The reaction of 4-aryl-3-thiosemicarbazides 1a-d with phenylisothiocyanate
gave the intermediate potasium salts 2a-d. The latter afforded 3a-d, 13a-d
and 19 upon the reaction with phenacyl bromide, monochloroacetic acid and e
thyl bromocyanoacetate respectively.