Endobronchial metastasis of glioblastoma multiforme diagnosed by fiberoptic bronchoscopic biopsy

The report a case of extraneural metastasis of an intracranial glioblastoma multiforme (GBM) to the left upper lung, in which fiberoptic bronchoscopy played a key hole in the diagnosis. The patient, a 20-year-old woman, prese nted with dry cough and hoarseness 2 years after total excision of the brai n tumor and postoperative radiotherapy. Tissue samples obtained during fibe roptic bronchoscopic biopsy had the same morphologic appearance as the prim ary intracranial tumor, which was consistent with GBM. In cases of pulmonar y metastasis of GBM, antemortem diagnosis is rare. Our experience from this case suggests that GBM fiberoptic bronchoscopy may he a valuable diagnosti c tool for metastatic GBM.