A female Shetland sheep dog died suddenly with hemorrhagic diarrhea and vom
itting, and was examined pathologically and microbiologically. Gross pathol
ogical change was restricted to the intestinal tract. The intestine contain
ed watery, blood-stained fluid. Histopathologically, the principal intestin
al lesion was superficial mucosal hemorrhagic necrosis at the jejunoileum.
Many Gram-positive bacilli were found adhering to the necrotic mucosal surf
ace in parts of the intestinal tract. Clostridium perfringens in pure cultu
re were isolated from jejunal contents by anaerobic culture. These results
suggested that the typical lesion of this case coincided with canine hemorr
hagic enteritis and enterotoxemia due to C. perfringens infection could be
the cause of sudden death. perfringens, enterotoxemia, hemorrhagic enteriti
s.