A malignant basal cell tumor was found in the skin of the abdomen of a fema
le Djungarian hamster of unknown age and weighing 40 g. Histologically, the
tumor mass was composed of cells resembling the basal cells of the epiderm
is, and these cells exhibited solid type proliferation. In the tumor tissue
and necrotic foci, horn cysts were observed. Immunohistochemically, cytoke
ratin was present in the tumor cells and horncysts. By electron microscopic
examination, the tumor cells had scanty cell organelles and a few desmozom
es. This paper describes a rare malignant basal cell tumor in a Djungarian
hamster.