IR-spectroscopy for tissue differentiation in the medical field

IR-microspectrascopy is a powerful and reliable analytical tool. This metho d has not yet been used clinically for diagnostic or therapeutical purposes . However, over the past few years, there have been many attempts to use th e potential of mid-IR-spectrascopy for tissue characterization and differen tiation, This work is based on the assumption that every diseased stage has its own specific infrared spectroscopic characteristics. Therefore, in coo peration with pathologists we examined unfixed, air dried thin tissue secti ons of adenocarcinoma of the colon in order to evaluate distinct wavelength s in transmission, ATR, and reflection modes.