Systemic lupus erythematosus complicated by necrotizing fasciitis

A case of necrotizing fasciitis (NF) is described in a 46-year-old woman wi th recent onset systemic lupus erythematosus (SLE). Deep-tissue infections are more common in SLE patients on high-dose corticosteroids, but, to our k nowledge, this is the second case described in association with SLE. Althou gh NF may initially be difficult to diagnose, the presence of marked system ic symptoms out of proportion to the local findings should suggest the corr ect diagnosis. NF diagnostic criteria, treatment and prognosis are discusse d.